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Endocrine Disruption - Example Papers

Endocrine Disruption


The endocrine system is very dynamic and has ties to most, if not all of the other major systems of the body. It is responsible for production of hormones and the regulation of them as well. These hormones act as chemical messengers within the body. Through several differing mechanisms, they are able to trigger very specific responses in target cells or organs. This is what enables the endocrine system to guide growth, development, reproduction, and behavior, among many others as well.
The hormones produced from the endocrine system come from a wide range of different places. Among those responsible for hormone production are the glands and a few organs as well. The glands that are ...

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in a bottle. We can think of the body as a river, and a specific hormone may be a bottle containing a message. The organs or glands mentioned above would manufacture the “bottles” (hormones) that would be released into the river (blood stream). If there were no receptor sites for the hormones in the body, then they would continue to flow along the river and probably not make their destination. However, there are systems of receptor sites that enable specific hormones to bind in specific places. Structure also plays a major role in determining which hormones are able to bind to which receptors.
When these “messages in bottles” reach their appointed destination, the binding into the receptor site causes a cascade of reactions to occur. It is these reactions that are vital in maintaining our homeostasis. Many times the binding of the receptor site causes a direct expression of a certain gene. This is where endocrine disrupters can exert major ...

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are not needed and could be very harmful.
Another suspected mechanism is that the endocrine disrupting chemicals are just blocking the function of the natural hormone. This is in contrast to the mechanism above, where the disrupters are actually binding in the site the hormones usually would. This mechanism would produce a lower level of cellular responses, opposite of the first mechanism. There are a few other mechanisms that are thought to occur, but the majority of those we have discovered thus far fall under one of the two described above.
We have defined endocrine disrupters and given their two possible modes of action, but why exactly are we concerned with them? Endocrine ...

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PAPER DETAILS
Added: 10/11/2007 03:28:14 AM
Category: Science & Nature
Type: Premium Paper
Words: 2635
Pages: 10

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