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Huntington's Disease - College Essay

Huntington's Disease


, also known as Huntington's chorea is a genetic disorder
that usually shows up in someone in their thirties and forties, destroys the
mind and body and leads to insanity and death within ten to twenty years. The
disease works by degenerating the ganglia (a pair of nerve clusters deep in the
brain that controls movement, thought, perception, and memory) and cortex by
using energy incorrectly. The brain will starve the neurons (brain cells), and
sometimes make them work harder than usual, causing extreme mental stress. The
result is jerky, random, uncontrollable, rapid movement such as grimacing of the
face, flailing of arms and legs, and other such movement. This is known ...

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in a victim of Huntington's
disease the gene exists from anywhere between thirty-five to one-hundred or more.
The gene for the disease is dominant, giving children of victims of Huntington's
disease a 50% chance of obtaining the disease.

Several other symptoms of the disease exist other than chorea. High levels of
lactic acid have been detected in patients of Huntington's disease as a bi-
product of the brain cells working too hard. Also, up to six times above the
normal level of an important brain brain protein, bFGF (or basic fibroblast
growth factor) in areas of the brain effected by the chorea. This occurs from
the problems on chromosome 4, where the gene for control of bFGF is also located.


As of yet, there is no treatment for Huntington's disease. But with the
discovery of the mutated genes that cause it, there is now a way of diagnosing
if you will get it. This technique was discovered only recently and reported in
the Journal of American Medical Association in April, ...

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PAPER DETAILS
Added: 4/3/2008 05:23:00 PM
Category: Health & Medicine
Type: Premium Paper
Words: 1082
Pages: 4

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