Iron Absorption From The Whole Diet: Comparison Of The Effect Of Two Different Distributions Of Daily Calcium Intake

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amount of calcium intake is the increased
possibility of anemia in women who are already susceptible to this condition.
The iron inhibition by calcium is a classical example of how the correction of
one nutritional problem can be the cause of another.
The physiological mechanism of this calcium-iron relationship remains a
mystery, however there are two feasible theories. One states that calcium
competes for an iron binding site on intestinal epithelial cells. It is
believed calcium binds to the protein mobilferrin on the epithelial cells, which
is the iron transport protein(Whiting, p.78). Another group of scientists
theorizes that iron is able to be transported into the epithelial cells without
problem, however the iron then has trouble getting into the blood stream. The
presence of calcium inhibits iron’s ability to leave the epithelial layer.
Another very interesting theory is not on the microscopic level but in
the evolutionary plane. Eaton et al. state that one ...

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used as a control rate for each
subject.

Experiment - The absorption of nonheme was measured from all meals during four
5-d periods (A1, A2, B1, and B2). Each day four meals were served to the
subjects: breakfast, lunch, dinner, and an evening meal. The menu of the two B
weeks were identical to the two A weeks, except for the distribution of dairy
products. All meals, except for the evening meal, were served under supervision
in the lab. A precise measyre of the iron content of each meal was required to
enable the homogeneous labeling of the nonheme iron with radioisotopic iron.
One wheat-rye roll served as the carrier of the radioisotope, and this was eaten
throughout the course ...

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