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Limonene And Its Uses - College Papers

Limonene And Its Uses


United States Prevention, Pesticides EPA-738-F-94-030 Environmental
Protection And Toxic Substances September 1994 Agency (7508W)
R.E.D. FACTS Limonene
Pesticide Reregistration

All pesticides sold or distributed in the United States must be
registered by EPA, based on scientific studies showing that they can be
used without posing unreasonable risks to people or the environment.
Because of advances in scientific knowledge, the law requires that
pesticides which were first registered years ago be reregistered to ensure
that they meet today's more stringent standards.

In evaluating pesticides for reregistration, EPA obtains and
reviews a complete set of studies from ...

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in the RED document for
reregistration case 3083, limonene.

Use Profile

Limonene is a naturally occurring chemical which is used in many
food products, soaps and perfumes for its lemon-like flavor and odor.
Limonene also is a registered active ingredient in 15 pesticide products
used as insecticides, insect repellents, and dog and cat repellents.

Pesticide products containing limonene are used for flea and tick
control on pets, as an insecticide spray, an outdoor dog and cat repellent,
a fly repellent tablecloth, a mosquito larvicide, and an insect repellent
for use on humans. Formulations include ready-to-use solutions,
emulsifiable concentrates, granulars and impregnated material. Limonene is
applied by hand as needed, both indoors and outdoors. Use practice
limitations include a label prohibition against use on weanling kittens and
a caution against use of undiluted product.

Regulatory History

Limonene was first registered as a insecticide in the ...

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Limonene is of relatively low acute toxicity taken orally. It is a
dermal irritant when applied at high concentrations and may cause dermal
sensitization. A 90-day dermal toxicity study using the formulated product
is required as confirmatory data to support reregistration of the insect
repellent that is to be applied directly to human skin.

A subchronic study by the National Toxicology Program (NTP) using
rats and mice resulted in decreased body weights, kidney disease and
mortality at the highest dose tested. A chronic toxicity study by NTP using
rats resulted in decreased body weight, kidney disease and kidney tumors,
which occurred due to a species-specific mechanism. ...

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PAPER DETAILS
Added: 2/12/2004 07:00:59 PM
Category: Science & Nature
Type: Premium Paper
Words: 1780
Pages: 7

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