Hemophilia 3

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less common.
The gene for hemophilia-A is located at Xq28 while the gene for hemophilia-B is located at Xq27.1-q27.2. There are about thirty other disorders associated with the Xq28 area including manic depression and favism. This must indicate that Xq28 includes many different genes which have not yet been isolated.
The primary symptom of hemophilia is uncontrolled bleeding. The disease can range in severity from a mild increase in bleeding, to massive bleeding from even a minor wound. Treatment involves blood or clotting factor transfusions, and this increases the risk of contracting HIV, hepatitis or other blood transmitted diseases. Since blood banks have started screening and treating blood for HIV, the infection rate has dropped to almost nothing. However,prior to 1985 almost half the hemophiliac population was infected with HIV.
Defects in the factor VIII gene are so numerous in type that doctors cannot easily test for each one of them. By doing a series of genetic tests a ...

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