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Treating Diabetes With Transplanted Cells - Online Term Paper

Treating Diabetes With Transplanted Cells

Seventy-five years ago the type of diabetes that affected children and
young adults was lethal. In the 1990's investigators found that a hormone, that
was produced in Islets of Langerhans, was not being produced in diabetes
patients. This hormone, called insulin, enables other cells to take up sugar
glucose from the blood for energy. Diabetes patients who were not making insulin
had glucose from food accumulating in the blood while other tissues were
starving. Their are two types of diabetes. Type 1 diabetes has ceased completely
from making insulin and the people who had this kind usually died. Type 2
diabetes still makes a little insulin so suffers of this type usually lived.
...

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naturally made insulin.
That's why a therapy that maintains glucose values within normal from
the begging is needed. An ideal treatment would be the implantation of islets.
This, in theory, would only have to be done once and would insure proper insulin
production. Successful grafts would also prevent diabete-related ills.
At Paul E. Lacy's lab, experiments have been done for twenty- five years
on such a process. At first they were just trying to understand the mechanics of
hormone secretion. To start this they needed a way to separate islet clusters
from the pancreas. These constitute only 2% of the entire pancreas, though, and
are scattered throughout it. In 1967 they found a solution and took the islets
from rats. These islets were transplanted in inbred rats to see if it would
control insulin production in diabetes patients. It was a success and kept blood
sugar levels normal. It even fixed early complications in the eyes and the
kidneys.
The next step was ...

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Treating Diabetes With Transplanted Cells. (2008, March 22). Retrieved January 22, 2025, from http://www.essayworld.com/essays/Treating-Diabetes-With-Transplanted-Cells/80934

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PAPER DETAILS

Added: 3/22/2008 04:31:39 PM
Category: Health & Medicine
Type: Free Paper
Words: 1248
Pages: 5

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